Boyack KW, Mane K, Borner K "Mapping medline papers, genes, and proteins related to melanoma research" Eighth International Conference on Information Visualization, Proceedings. IEEE Conference on Information Visualization - Proceedings 965-971, 2004.

[Eugene Garfield]

Kevin W. Boyack : boyack at viswave.com
Ketan Mane : kmane at indiana.edu
Katy Borner: katy at indiana.edu

FULL TEXT AVAILABLE AT :
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=14963238

TITLE    :   Mapping medline papers, genes, and proteins related to melanoma
             research
AUTHOR   :   Boyack KW, Mane K, Borner K

SOURCE    :  EIGHTH INTERNATIONAL CONFERENCE ON INFORMATION VISUALISATION,
             PROCEEDINGS
Editors: Banissi E, Borner K, Chen C, Dastbaz M, Clapworthy G, Faiola A,
Izquierdo E, Maple C, Roberts J, Moore C, Ursyn A, Zhang JJ
IEEE CONFERENCE ON INFORMATION VISUALIZATION - PROCEEDINGS
965-971, 2004

Document Type: Article     Language: English     Cited References: 12
Related Records
 ISI Web of Science for Citing Articles

Conference Information:
8th International Conference on Information Visualisation
London, ENGLAND, JUL 14-16, 2004

Abstract:
What is the structure of the research reported on melanoma? How has it
evolved over the last 40 years? Which parts of this research field are
correlated with the study of genes and proteins? Are there sudden increases
in the number of occurrences of certain gene or protein names, reflecting a
surge of interest? How are genes, protein and papers interconnected via
co-occurrence patterns?

This paper aims to provide answers to these questions by analyzing a data
set consisting of papers from Medline, genes from the Entrez Gene database,
and proteins from UniProt. Word burst detection and co-occurrence analyses
were both performed. The spatial layout algorithm VxOrd was applied to
create the very first map that shows papers, genes, and proteins and their
co-occurrence relationships. The results were validated by five domain
experts leading to a number of interesting facts pertaining to structure and
dynamics of the melanoma research field.

KeyWords Plus:
DISCOVERY

Addresses:
Boyack KW, VisWave LLC, Albuquerque, NM 87122 USA
VisWave LLC, Albuquerque, NM 87122 USA

Publisher:
IEEE COMPUTER SOC, 10662 LOS VAQUEROS CIRCLE, PO BOX 3014, LOS ALAMITOS, CA
90720-1264 USA

IDS Number:
BAQ15

ISSN:
1093-9547

ISBN:
0-7695-2177-0

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