Kenyon S., Taylor DJ. "The effect of the publication of a major clinical trial in a high impact journal on clinical practise: the ORACLE trial experience" BJOG: an International journal of Obstetrics and Gynaecology 109(12):1341-1343, December 2002

[Eugene Garfield]

TITLE :  The effect of the publication of a major clinical trial in a high
         impact journal on clinical practise: the ORACLE Trial experience
AUTHOR:  Kenyon S, Taylor DJ
JOURNAL: BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
         109 (12): 1341-1343 DEC 2002


 Document type: Article   Language: English
 Cited References: 17     Times Cited: 1

Abstract:
Objective To estimate the short term effect of the publication of a major
clinical trial on clinical practise.

Design Questionnaire survey of clinical practise.

Setting UK.

Population All maternity units in the UK.

Method A self-administered questionnaire completed by lead consultants on
delivery suite of maternity units.

Main outcome measures Changes in antibiotic prescription.

Results Within six months of publication, approximately 50% of maternity
units had changed their guidelines for the care of women with preterm
prelabour rupture of the fetal membranes.

Conclusion Publication of a major clinical trial does impact on clinical
practise but the impact is heterogeneous in terms of time and consistency.

KeyWords Plus:
BROAD-SPECTRUM ANTIBIOTICS, PRELABOR RUPTURE, RANDOMIZED TRIAL, PRETERM,
MANAGEMENT, MEMBRANES, LONDON,
LABOR

Addresses:
Kenyon S, Leicester Royal Infirm, Robert Kilpatrick Clin Sci Bldg,POB 65,
Leicester LE2 7LX, Leics, England
Leicester Royal Infirm, Leicester LE2 7LX, Leics, England

Publisher:
ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS

IDS Number:
629RR

ISSN:
1470-0328


 Cited Author            Cited Work                Volume      Page   Year

                       LANCET                       340      1387      1992
 ANTMAN EM             JAMA-J AM MED ASSOC          268       240      1992
 BERO LA               BRIT MED J                   317       465      1998
 CROWLEY P             BRIT J OBSTET GYNAEC          97        11      1990
 DONALDSON LJ          BRIT MED J                   305      1280      1992
 DULEY L               LANCET                       345      1455      1995
 GUERRANT RL           NEW ENGL J MED               325       327      1991
 GULMEZOGLU AM         BRIT MED J                   316       975      1998
 HAINES A              BRIT MED J                   317        72      1998
 HANNAH ME             NEW ENGL J MED               334      1005      1996
 JONES K               BRIT J GEN PRACT              41       224      1991
 KENYON SL             LANCET                       357       979      2001
 KENYON SL             LANCET                       357       989      2001
 KURJI KH              BRIT MED J                   288       903      1984
 LAVERICK MD           BRIT MED J                   303       549      1991
 MOSTELLER F           SCIENCE                      211       881      1981
 SMITH WCS             BRIT MED J                   300       981      1990

_______________________________________________________________________
Eugene Garfield, PhD.  email: garfield at codex.cis.upenn.edu
home page: www.eugenegarfield.org
Tel: 215-243-2205 Fax 215-387-1266
President, The Scientist LLC. www.the-scientist.com
Chairman Emeritus, ISI www.isinet.com
Past President, American Society for Information Science and Technology
(ASIS&T)  www.asis.org
_______________________________________________________________________