Lopez-Munoz F, Alamo C, Rubio G, Garcia-Garcia P, Martin-Agueda B, Cuenca E "Bibliometric analysis of biomedical publications on SSRIs during 1980-2000" DEPRESSION AND ANXIETY 18 (2): 95-103 2003

[Eugene Garfield]

Lopez-Munoz F. :  frlopez at juste.net

TITLE    Bibliometric analysis of biomedical publications on SSRIs
         during 1980-2000
AUTHOR   Lopez-Munoz F, Alamo C, Rubio G, Garcia-Garcia P,
         Martin-Agueda B, Cuenca E
JOURNAL  DEPRESSION AND ANXIETY 18 (2): 95-103 2003


 Document
 type: Article Language: English    Cited references: 23  Times Cited: 0

Abstract:
We performed a bibliometric study of the scientific publications referring
to selective serotonin reuptake inhibitors (SSRIs). The database used was
EMBASE: Psychiatry. We applied the principal bibliometric indicators:
Price's and Bradford's laws on the increase or dispersion of scientific
literature, Lotka's law on the productivity of authors, the participation
index (Pal) of countries, the productivity index (PI) of authors, and
the collaboration index. By means of manual coding, documents were
classified according to type of study and to the Diagnostic and Statistical
Manual of Mental Disorders, Fourth Edition (DSM-IV) or nonpsychiatric
categories. We analysed 3,622 original documents published between 1980 and
2000. Our results show nonfulfilment of Price's law because production on
SSRIs does not grow exponentially (r = 0.937 vs. r = 0.946, after linear
adjustment). The journal most employed is the journal of Clinical Psychiatry
(Bradford's first zone). The United States is the most productive country
(PaI = 41.50). The documents were distributed in four groups: experimental
pharmacology (8.38%), tolerance and safety (34.94%), clinical efficacy
(49.11%), and not specified (7.56%). The drug most studied was fluoxetine
(1,745 articles), followed by paroxetine (659). The DSM-IV diagnostic
categories most studied were depression (834), obsessive-compulsive disorder
(171), and panic disorder (75). The control antidepressants most used in
comparative clinical studies were amitriptyline (51) and imipramine (42).
The results of the present study show that the SSRIs are not solely
antidepressant drugs, but also have a wide range of uses both within the
psychiatric sphere (especially in the field of anxiety) and outside it,
which explains the considerable scientific production generated in relation
to these drugs. (C) 2003 Wiley-Liss, Inc.

Author Keywords:
SSRIs, antidepressants, anxiolytics, bibliometry

KeyWords Plus:
ANTIDEPRESSANT USE, PANIC DISORDER, DEPRESSION, PHARMACOTHERAPY

Addresses:
Lopez-Munoz F, Univ Alcala De Henares, Dept Pharmacol, Neuropsychopharmacol
Unit, C Juan Ignacio
Luca Tena 8, Madrid 28027, Spain
Univ Alcala De Henares, Dept Pharmacol, Neuropsychopharmacol Unit, Madrid
28027, Spain
Madrid Autonom Community Govt, Hlth Council, Dept Psychiat & Mental Hlth,
Madrid, Spain

Publisher:
WILEY-LISS, DIV JOHN WILEY & SONS INC, 605 THIRD AVE, NEW YORK, NY
10158-0012
USA

IDS Number:
726HJ


 Cited Author            Cited Work                Volume      Page   Year
     ID

 ALAMO C               10 WORLD C PSYCH AUG                   288      1996
 ALAMO C               10 WORLD C PSYCH AUG                   314      1996
 ALAMO C               PSICHIATRIA MED                2         1      1998
 BRADFORD SC           DOCUMENTATION                                   1948
 CUENCA E              TRASTORNOS NEUROTICO                   823      2002
 DENBOER JA            J CLIN PSYCHIAT S8            59        30      1998
 DEVANE CL             AM J MED S6A                  97        13      1994
 GANGULI M             J AM GERIATR SOC              45      1501      1997
 HENRY JA              PHARMACOECONOMICS             11       419      1997
 JOHNSON RE            PHARMACOECONOMICS             11       274      1997
 KECK PE               J CLIN PSYCHIAT S14           58        32      1997
 LOOSBROCK DL          PSYCHIATR SERV                53       179      2002
 LOPEZIBOR JJ          EUR PSYCHIAT                  15       362      2000
 LOPEZIBOR JJ          PRIMARY CARE PSYCHIA           5       133      1999
 LOPEZMUNOZ F          HIST NEUROPSICOFARMA                   269      1998
 LOPEZMUNOZ F          J MED EC                       1       177      1998
 LOPEZPINERO JM        MED CLIN-BARCELONA            98       384      1992
 LOTKA AJ              J WASHINGTON ACADEMY          16       317      1926
 MULLER HJ             DRUGS                         52       625      1996
 PRICE DJS             LITTLE SCI BIG SCI                              1993
 SHEEHAN DV            J CLIN PSYCHIAT S10           57        51      1996
 SKAER TL              CNS DRUGS                     14       473      2000
 VALLEJO J             ANTIDEPRESIVOS CLIN                     55      1996


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_______________________________________________________________________
Eugene Garfield, PhD.  email: garfield at codex.cis.upenn.edu
home page: www.eugenegarfield.org
Tel: 215-243-2205 Fax 215-387-1266
President, The Scientist LLC. www.the-scientist.com
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(ASIS&T)  www.asis.org
_______________________________________________________________________



ISSN:
1091-4269