Robert, C; Wilson, CS; Gaudy, JF; Hornebeck, W; Arreto, CD. 2010. Trends in matrix metalloproteinase research from 1986-2007: a bibliometric study. BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE 88 (5): 843-851

[Eugene Garfield]

Robert, C; Wilson, CS; Gaudy, JF; Hornebeck, W; Arreto, CD. 2010. Trends in 
matrix metalloproteinase research from 1986-2007: a bibliometric study. 
BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE 88 (5): 
843-851.

Author Full Name(s): Robert, Claude; Wilson, Concepcion S.; Gaudy, Jean-
Francois; Hornebeck, William; Arreto, Charles-Daniel

Language: English
Document Type: Article

Author Keywords: matrix metalloproteinase; MMP; journal analysis; cancer 
research; bibliometrics
KeyWords Plus: TADPOLE COLLAGENASE; TISSUE INHIBITORS; SCIENCE; 
CANCER; PROGRESSION; TARGETS; WORLD

Abstract: Using the SCI-expanded database, this study provides a quantitative 
description of the development of the research involving matrix 
metalloproteinase (MMP) over a period of 20 years. From 1986 to 2007 the 
scientific literature related to MMP increased sevenfold (397 papers in 1986-
1987 and 2834 in 2006-2007). The number of countries participating in MMP-
related research doubled during this period (33 in 1986-1987 to 67 in 2006-
2007), and the USA continually remained the leader. Several industrialized 
nations (Japan, Germany, UK, Canada, and France) also continuously played 
important roles, with some emerging Asian countries joining the top 10 most 
productive countries in 20062007: China (ranked 5th), South Korea (6th), and 
Taiwan (10th). The MMP-related literature was distributed among a 
continuously growing number of journals (188 in 1986-1987, 527 in 1996-1997, 
and 913 in 2006-2007) and The Journal of Biological Chemistry remained the 
most prolific throughout the entire period. The development of the research 
involving MMPs during the past two decades was also characterized by a 
progressive transfer of interest from basic research to clinical medicine; cell 
biology and pharmacology were important routes of investigation generally 
pursued by researchers. Journals dedicated to oncology have progressively 
risen to the top 8 most prolific journals during the 20 year period analyzed.

Addresses: [Robert, Claude; Gaudy, Jean-Francois; Arreto, Charles-Daniel] Univ 
Paris 05, Fac Chirurg Dent, Lab Anat Fonct, F-92120 Montrouge, France; 
[Wilson, Concepcion S.] Univ New S Wales, Sch Informat Syst Technol & 
Management, Sydney, NSW, Australia; [Hornebeck, William] Univ Reims, ICMR 
UMR 6229, CNRS, Fac Pharm, F-51095 Reims, France

Reprint Address: Robert, C, Univ Paris 05, Fac Chirurg Dent, Lab Anat Fonct, 1 
Rue Maurice Arnoux, F-92120 Montrouge, France.

E-mail Address: claude.robert at parisdescartes.fr
ISSN: 0829-8211
DOI: 10.1139/O10-006
URL (not fulltext): http://rparticle.web-
p.cisti.nrc.ca/rparticle/AbstractTemplateServlet?
calyLang=eng&journal=bcb&volume=88&year=0&issue=5&msno=o10-006