Willett, P (Willett, Peter) From chemical documentation to chemoinformatics: 50 years of chemical information science JOURNAL OF INFORMATION SCIENCE, 34 (4): 477-499 AUG 2008

[Eugene Garfield]

E-mail Address: p.willett at sheffield.ac.uk 

Author(s): Willett, P (Willett, Peter) 

Title: From chemical documentation to chemoinformatics: 50 years of 
chemical information science 

Source: JOURNAL OF INFORMATION SCIENCE, 34 (4): 477-499 AUG 2008 

Language: English
 
Document Type: Review 

Author Keywords: chemical documentation; chemical structures; 
chemoinformatics; drug discovery; history; informatics; molecules; 
pharmaceutical research 

Keywords Plus: COMPUTER-ASSISTED DESIGN; UNIVERSITY-OF-SHEFFIELD; DRUG 
DISCOVERY; ABSTRACTS-SERVICE; SEARCH SYSTEM; COMBINATORIAL LIBRARIES; 
SUBSTRUCTURAL ANALYSIS; BIOLOGICAL-ACTIVITY; GENETIC ALGORITHM; ARTIFICIAL-
INTELLIGENCE 

Abstract: This paper summarizes the historical development of the 
discipline that is now called ` chemoinformatics'. It shows how this has 
evolved, principally as a result of technological developments in 
chemistry and biology during the past decade, from long- established 
techniques for the modelling and searching of chemical molecules. A total 
of 30 papers, the earliest dating back to 1957, are briefly summarized to 
highlight some of the key publications and to show the development of the 
discipline. 
Addresses: Univ Sheffield, Dept Informat Studies, Sheffield S1 4DP, S 
Yorkshire, England 
Reprint Address: Willett, P, Univ Sheffield, Dept Informat Studies, 211 
Portobello St, Sheffield S1 4DP, S Yorkshire, England. 

Cited Reference Count: 182 

Times Cited: 0 

Publisher: SAGE PUBLICATIONS LTD 

Publisher Address: 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND 

ISSN: 0165-5515 

DOI: 10.1177/0165551507084631 

29-char Source Abbrev.: J INFORM SCI 

ISO Source Abbrev.: J. Inf. Sci. 

Source Item Page Count: 23 

Subject Category: Computer Science, Information Systems; Information 
Science & Library Science 

ISI Document Delivery No.: 334XN 

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